Sam Winchester references The Brady Bunch in the Pilot. Sam compares his family to the idealized Brady family.

Luis references The Cosby Show in the Pilot. Luis answers with the Huxtable family from The Cosby Show.

Dean Winchester references The Smurfs in the Pilot. Dean explicitly names The Smurfs as part of a joke.

Sam Winchester references Metallica in the Pilot. Sam explicitly names Metallica while mocking Dean's cassette collection.

Dean Winchester references The X-Files in the Pilot. Dean directly invokes The X-Files agents Mulder and Scully.

Dean Winchester references Unsolved Mysteries in the Pilot. Dean explicitly names the paranormal television series.